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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vclsl</journal-id><journal-title-group><journal-title xml:lang="ru">Ветеринарные клинические случаи</journal-title><trans-title-group xml:lang="en"><trans-title>Veterinary Clinical Cases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0000-0000</issn><issn pub-type="epub">0000-0000</issn><publisher><publisher-name>https://donstu.ru/</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vclsl-3</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ВЕТЕРИНАРНАЯ ХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>VETERINARY SURGERY</subject></subj-group></article-categories><title-group><article-title>Бактериальное осложнение после хирургического вмешательства, вызванное мультирезистентным штаммом Staphylococcus pseudintermedius (MRSP)</article-title><trans-title-group xml:lang="en"><trans-title>Bacterial Complication after Surgery Caused by a Multidrug-Resistant Strain of Staphylococcus pseudintermedius (MRSP)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лаврова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lavrova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Екатерина Александровна Лаврова, ветеринарный врач, интерн 1-го года обучения по специальности «Дерматология» Донского государственного технического университета</p><p>344003, г. Ростов-на-Дону, пл. Гагарина, 1</p></bio><bio xml:lang="en"><p>Ekaterina A. Lavrova, veterinarian, 1st-year intern in the specialty “Dermatology”, Don State Technical University</p><p>344003, Rostov-on-Don, Gagarin Square, 1</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ветеринарная клиника Dr.Pets, г. Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Veterinary clinic Dr.Pets, St. Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>05</day><month>09</month><year>2026</year></pub-date><volume>1</volume><issue>1</issue><fpage>7</fpage><lpage>19</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лаврова Е.А., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Лаврова Е.А.</copyright-holder><copyright-holder xml:lang="en">Lavrova E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vetclincases.ru/jour/article/view/3">https://www.vetclincases.ru/jour/article/view/3</self-uri><abstract><sec><title>Введение</title><p>Введение. Опухоли тучных клеток (ОТК) считаются наиболее распространенными кожными новообразованиями у собак. Они составляют 16–21 % всех дерматологических неоплазий у данного вида, как правило, требуя широкого радикального иссечения. Несмотря на рутинность подобного оперативного вмешательства, постоперационные последствия встречаются часто из-за специфического биологического поведения патологии, особенностей техники проведения процедуры, а также высокой вероятности присоединения вторичной микрофлоры. Цель публикации подробно описать редкий клинический прецедент, наряду с этим акцентировать внимание практикующих врачей на актуальной проблеме возрастающего распространения мультирезистентных штаммов Staphylococcus. pseudintermedius . Развитие инфекции кожи как раннего послеоперационного осложнения резекции низкодифференцированной мастоцитомы, вызванной полирезистентным штаммом S. pseudintermedius у собак, ранее не описывалось на территории Российской Федерации.</p><p>Описание клинического случая. Пациент собака нестандартной породы (метис), интактный самец в возрасте 8 лет. Животное поступило с жалобами владельцев на вялость, выраженную болезненность, отек и покраснение кожных покровов в области головы и левой ушной раковины. Данные симптомы возникли вокруг послеоперационного шва в течение 72 часов после проведения экстирпации низкодифференцированной мастоцитомы. Патологический процесс стремительно развивался на фоне стандартной антибиотикотерапии препаратом амоксициллина с клавулановой кислотой. При общем объективном осмотре была выявлена гипертермия (температура тела 39,7 °С), значительный отек, эритема, экссудация вокруг хирургической раны с переходом воспаления на мягкие ткани ушной раковины. В ходе пальпации пораженных участков отмечалась сильная болевая реакция. Первоначальный диагноз был установлен на основании собранного анамнеза, манифестации симптомов и результатов предварительного цитологического исследования. После замены антибактериального препарата, еще до получения итоговых данных бактериологического исследования, были зафиксированы выраженные позитивные сдвиги в состоянии пациента. Впоследствии окончательный диагноз полностью подтвердился результатами микробиологического исследования.</p></sec><sec><title>Обсуждение</title><p>Обсуждение. Представленный материал наглядно доказывает возможность развития послеоперационных бактериальных патологий, ассоциированных с мультирезистентной микрофлорой в реалиях современной ветеринарной практики. Данный факт прямо актуализирует вопрос о необходимости и целесообразности отказа от рутинного использования защищенных бета-лактамных антибиотиков в качестве терапевтических средств первого выбора при дерматологических хирургических вмешательствах.</p></sec><sec><title>Заключение</title><p>Заключение. Полученные аналитические данные могут быть в дальнейшем успешно использованы для инициации масштабных исследований частоты встречаемости антибиотикорезистентных штаммов бактерий в ветеринарных клиниках нашей страны. Это абсолютно необходимо для последующей разработки эффективных мер строгой профилактики внутрибольничного заражения пациентов.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Mast cell tumors (MCTs) are the most common skin tumors in dogs, accounting for 16% to 21% of all skin neoplasms in this species, requiring extensive surgical excision. Despite the routine nature of this surgical procedure, surgical complications are common due to the biological behavior of the tumor, the specific surgical technique, and the possibility of bacterial complications. The purpose of this publication is to describe a clinical case and highlight the increasing prevalence of multidrug-resistant Staphylococcus pseudintermedius strains. To the author's knowledge, clinical cases of bacterial skin infection caused by a multidrug-resistant S. pseudintermedius strain, which arose as an early postoperative complication following surgical removal of a poorly differentiated mastocytoma, have not previously been described in dogs in the Russian Federation.</p><p>Description of a clinical case. The patient, an intact male mixed-breed dog, 8 years old, was admitted with complaints of lethargy, severe pain, swelling, and redness of the skin around the head and left ear. Symptoms developed in the area of the postoperative incision within 72 hours after surgical removal of a low-differentiated mastocytoma during antibiotic therapy with amoxicillin and clavulanic acid. A general examination revealed hyperthermia (39.7 °C), severe swelling, erythema, and exudation around the surgical incision extending to the auricle tissue. Palpation of the affected areas revealed tenderness. The diagnosis was suggested based on the patient's history, clinical presentation, and cytological examination results. After changing the antibiotic and before receiving culture results, significant clinical improvements were noted. The diagnosis was confirmed by culture results.</p></sec><sec><title>Discussion</title><p>Discussion. This clinical case confirms the possibility of postoperative bacterial complications associated with multidrugresistant strains in modern veterinary practice and highlights the need for and feasibility of abandoning the use of protected B-lactam antibiotics as first-line treatments.</p></sec><sec><title>Conclusion</title><p>Conclusion. The data obtained can be used to initiate further research into the prevalence of resistant bacterial strains in veterinary clinics in our country to further develop infection prevention measures.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>Staphylococcus pseudintermedius</kwd><kwd>MRSP</kwd><kwd>бактериальная инфекция кожи</kwd><kwd>бактериальное осложнение</kwd><kwd>мастоцитома кожи</kwd><kwd>мультирезистентный штамм</kwd><kwd>собака</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Staphylococcus pseudintermedius</kwd><kwd>MRSP</kwd><kwd>bacterial skin infection</kwd><kwd>bacterial complication</kwd><kwd>skin mastocytoma</kwd><kwd>multi-resistant strain</kwd><kwd>dog</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ribeiro PR, Bianchi MV, Bandinelli MB et al. 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